商品介紹

Sonitron GTS Sonoporation System

Ultrasound Transfection and Drug Delivery

超音波基因/藥物傳送儀

  • 操作簡便且效率高的非病毒式超音波傳送法

  • 藉由 W/cm², duty cycle rate 及時間設定等參數來調整條件

  • 可選用plane wave 或HIFU transducers以搭配 in vivo 及 in vitro 實驗

  • 1mm, 3mm, 6mm, 12mm, 20mm 外徑大小的 plane 探頭 與 20mm or 30mm內徑大小的HIFU探頭供選

 

應用:

  1. In Vivo Transfection

  * into mice/rats:brain, spinal cord, retina, cornea, ear, gingiva, salivary gland, lung, liver, kidney, peritonea, spleen, intestine, vessel, arthro,skin, embryos etc.

   2. In Ovo Transfection

   * into chick embryos

   3. Cell Culture Transfection

   * into Hela, KATOⅢ, MKN-45, CHO, NIH/3T3, HL-60, C1271, T24, Mouse ascites, Rat bladder, PC3, U937 and more

 

特點: 

* Safety Transfection

Sonitron GTS is the device which can introduce gene or medicine into cells by means of cavitation generated by ultrasound and there is little damage to the cells. This technique is called "Sonoporation". Because ultrasound is used in clinical use, the sonoporation method is suitable for research that would be developed for clinical use.

* Interchangeable Transducer Module

The transducer module is interchangeable without a calibration work, because the Sonitron GTS can self-calibrate our transducers.

* Focused UltraSound (FUS) Reserach

With the High Intensity Focused Ultrasound (HIFU) transducer module, the Sonitron GTS can be used for FUS research.

* Combination with Microbubbles

The Sonitron GTS makes it possible to achieve higher transfection efficiency in combination with microbubbles. Besides, it can target specific cells with the use of special microbubbles such as Targesphere SA (Targeson Inc.)

 

探頭模組:

A variety of transducer sizes are available. The transducer modules can be easily swapped

Photos: Plane Wave Transducer Module 3mm diameter tip and Basestation

 

Plane Wave Transducers:

PW-1.0-1mm: Plane Wave Transducer Module, 1mm diameter tip, 1MHz PW-1.0-3mm: Plane Wave Transducer Module, 3mm diameter tip, 1MHz PW-1.0-6mm: Plane Wave Transducer Module, 6mm diameter tip, 1MHz      PW-1.0-12mm: Plane Wave Transducer Module, 12mm diameter tip, 1MHz      PW-1.0-20mm: Plane Wave Transducer Module, 20mm diameter tip, 1MHz

 

HIFU Transducers:

HIFU-3.5-50mm: HIFU Transducer Module, 30mm diameter, 3.5MHz, 50mm focal depth HIFU-2.2-19mm: HIFU Transducer Module, 20mm diameter, 2.2MHz, 19mm focal depth

 

 

規格:

Frequency	Plane Wave Transducers: 1MHz HIFU Transducers: 2.2MHz, 3.5MHz Available range: 800k - 8MHz
Ultrasound Intensity	Plane Wave Transducers: 0.01-0.5W/cm2 or 0.1-5W/cm2 HIFU Transducers: 10-200W/cm2 or 100-2000W/cm2
Duty Cycle	On: 1～20, Off: 0～20, msec or sec
Treatment time	0-20 min
Preset	18 preset conditions
Power source	Setting 1 (default): 100V/50Hz, 110V/60Hz, Setting 2: 230V/50Hz
Dimensions, Weight	310W x 230D x 140H mm, 5kg